A new study compares a generic worm treatment called Noromectin to the proven brand name drug Ivermectin. These two insecticides are both effective against gastrointestinal nematodes, which are responsible for compromising bovine herds’ immunity, health and fertility. In this study, fecal egg counts were conducted to determine which drug was more effective, and larval cultures were conducted to identify species resistant to both drugs.
Despite their different effectiveness, ivermectin does have some drawbacks, including the risk of gastrointestinal side effects. Patients taking the drug should discuss the side effects with their healthcare provider, as there are unknown interactions with other medications. If you are breastfeeding, it is important to discuss your current medications with your doctor, because ivermectin can cause adverse reactions in nursing infants. If you are breastfeeding, you should stop taking this drug if you are nursing your baby. However, this may be risky if you are already breastfeeding or if you are pregnant or lactating. It’s important to discuss this drug’s safety with your physician if you’re nursing a baby.
Ivermectin belongs to the macrocyclic lactone endectocide class. It works by selectively binding to glutamate-gated chloride ion channels in invertebrates. When these channels are blocked, the parasites are paralyzed. In swine, this compound can also interact with GABA-gated chloride channels, but only after the dose has been doubled. Ivermectin has a high toxicity threshold. It is recommended for use in humans, while noromectin is approved for use in livestock.
Cattle and swine are treated using Noromectin Injection, which is given subcutaneously. One mL contains ten milligrams of ivermectin per kilogram of body weight. Noromectin Multi Injection is also used in young pigs, with 0.1ml of injection administered per three-kilogram body weight. However, it is important to note that cattle must wait 49 days after the previous treatment. Also, pregnant heifers should not receive Noromectin Multi Injection, and dairy cows must wait 49 days after the last treatment.
In the United States, cattle are treated with Noromectin Injection for gastrointestinal worms and lungworms. In pigs and cattle, a single dose of Noromectin contains 200 milligrams of ivermectin per kilogram of body weight. Noromectin Injection is also used in humans and can be given subcutaneously into the neck.